The formula and preparation method of homemade hand disinfectant and decision tree recommended by the community pharmacist

Source: International Pharmacy Federation

WHO recommends homemade hand disinfection formula

1. Formula and concentration:



1. Glycerin: As a moisturizing agent, other cheap, easy to obtain, easy to dissolve with water or alcohol, and does not increase toxic or sensitivity can be used for skin care.


2. Hydrogen dioxide solution: For the bacterial spimli in the inactivated solution, it is not an active ingredient for hand disinfection.

3. The coloring agent can be added to distinguish from other liquids, but toxicity and sensitivity should not be added, and their antibacterial properties should not be affected.

4. Considering the risk of allergens, it is not recommended to add fragrance agents and dyes.

2. Preparation method:

1. Total amount: 10L.

2. Reagents and dosage:

3. Preparation steps

Step 1: Pour alcohol into the container until the corresponding scale line.


Step 2: Add a hydrogen peroxide solution with the corresponding capacity.

Step 3: Add the corresponding capacity glycerin with a measuring cylinder. Because gly glycerin is sticky to adhere to the tube wall, it should be transferred to the container with sterile distillation or rinse after boiling cold water.


Step 4: Use sterile distillation or boiled cold water to add a container until the 10L scale.


Step 5: After preparing, cover the container to prevent evaporation.

Step 6: Gently shake to mix the solution.

Step 7: Immediately packaged into the finished container (such as: 500ml or 100ml plastic bottle). Before use, it should be isolated for 72 hours to ensure that the spores existing in the container are killed.


3. Quality control

1. Corresponding analysis should be performed before each production, and some self -made products cannot guarantee its purity. The use of alcohol proportion to verify the concentration of alcohol, and if necessary, the formula should be appropriately adjusted according to its actual concentration to ensure its finished product concentration.

2. After the use of ethanol or isopropanol, production must be performed after production. The use of alcohol proportion controls its finished alcohol concentration, and its error shall be controlled at the target concentration ± 5%(75%-85%of ethanol concentration).


3. The proportion of alcohol is used for ethanol measurement; if it is required for isopropanol measurement, the display scale of 75%solution at 25 ° C is 77%(± 1%).

Fourth, label


It needs to meet the requirements of national standards and include the following:


1. Institutional name


2. WHO recommendation hand disinfection formula formula

3. Only external use

4. Avoid contact with the eyes

5. Put in places where children cannot contact


6. Production date and batch number

7. Use: each time a sterilizer is used to use a handy hand to cover all the skin of the hand and rub the hand until it is dry.

8. Ingredients: ethanol or glycol, glycerol, hydrogen peroxide


9, flammable material: stay away from Minghuo and thermal source

5. Production and storage

1. Ideally, its production and storage should be carried out in rooms with low air conditioners or low temperatures. The area should be prohibited from open fire or smoking.

2. WHO recommends hand disinfection liquid formula for a single preparation should not exceed 50L, and cannot be performed in central pharmacies without special air conditioners and ventilation equipment.


3. Due to the high flammable ethanol, it may be ignited when it is lower than 10 ° C. During the production process, it should be diluted directly to the required concentration. The flash point of 80%(V/V) ethanol is 17.5 ° C, and the flash point of 75%(V/V) isopropanol is 19 ° C.


4. The storage of raw materials and finished products should comply with national security standards and local laws.

Decision tree recommended by community pharmacists

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